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UK Health Security Agency

About

The UK Health Security Agency (UKHSA) will be responsible for planning, preventing and responding to external health threats, and providing intellectual, scientific and operational leadership at national and local level, as well as on the global stage. UKHSA will ensure the nation can respond quickly and at greater scale to deal with pandemics and future threats.

Contact

Address: 10 South Colonnade; London; E14 4PU

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Open

Ref: 919-CA-302673-EXT Vacancy ID: 7570637

Programme Lead, Experimental Toxicology

Accepting applications until: 25-Nov-2025 23:59

Vacancy status: Open

Accepting applications until: 25-Nov-2025 23:59

Location

Gwefan: Chilton (Didcot)
Tref: Oxford
Cod post: OX11 0RQ
Major / Minor Region: London

Contract type & working pattern

Contract

Permanent

Oriau

Full time
Part time
Job share
Flexible working

37.5 hours per week

Salary

Cyflog: £72,950 - £83,443 per annum pro rata
Cyfnod cyflog: Yearly
Gradd: (Civil Service: Grade 6)

Specialty

Prif leoliad: Toxicology

The United Kingdom Health Security Agency (UKHSA) is a system leader for health security; taking action internationally to strengthen global health security, providing trusted advice to government and the public and reducing inequalities in the way different communities experience and are impacted by infectious disease, environmental hazards, and other threats to health.

UKHSA’s remit, as an agency with a global-to-local reach, is to protect the health of the nation from infectious diseases and other external threats to health. As the nation’s expert national health security agency UKHSA will:

Prevent: anticipate threats to health and help build the nation’s readiness, defences and health security
Detect: use cutting edge environmental and biological surveillance to proactively detect and monitor infectious diseases and threats to health
Analyse: use world-class science and data analytics to assess and continually monitor threats to health, identifying how best to control and mitigate the risks
Respond: take rapid, collaborative and effective actions nationally and locally to mitigate threats to health when they materialise
Lead: lead strong and sustainable global, national, regional and local partnerships designed to save lives, protect the nation from public health threats and reduce inequalities.

Swydd-ddisgrifiad a phrif gyfrifoldebau manwl

To contribute to the development of UKHSA’s Toxicology strategy and research and innovation functions including but not limited to the provision of:

Leadership and management of an expert, skilled team of toxicologists and associated scientists as appropriate
Being responsible on a day-to-day basis for the provision of toxicological analyses and outputs
Further development and provision of maintenance of services to support response and research for colleagues across the organisation and government
Working with internal and external stakeholders across UKHSA, DHSC and Whitehall and international organisations, including OECD, for development and provision of advice, services and analyses
Development of data sharing and publication initiatives
Representation of the Experimental Toxicology team functions at a strategic level

Responsibility for appropriate documentation, quality assurance, and information governance of Experimental Toxicology processes and data

Other

• The above is only an outline of the tasks, responsibilities and outcomes required of the role. You will carry out any other duties as may reasonably be required by your line manager.

• The job description and person specification may be reviewed on an ongoing basis in accordance with the changing needs of the division and the UKHSA.

• It should be noted that the work of the division is of a confidential nature and must not be communicated to other persons except where required for authorised purposes.

This post is a leadership role in the Experimental Toxicology team of the Toxicology department. The postholder will lead a comprehensive experimental toxicology programme enabling the team to develop and apply cutting edge toxicological methods and tools to inform public health decision making, with a particular focus on environmental hazards to human health and chemical hazard test method development, including in vitro methods.

Work within the Experimental Toxicology team is varied, responding to changing public health needs through research and response activities.

Functions and objectives of the team include:

Lead on the research, provision and application of advanced toxicological models and methods in support of advice provision in response to chemical and other environmental hazards, research and chemicals regulation
Manage, develop, and maintain appropriate toxicology laboratories and specialist equipment for undertaking specialist toxicological model and method development and using environmental and biological sample analysis to support the functions above
Manage, develop and maintain toxicology research capability to support chemical regulation and research on chemical and environmental hazards and exposures
Undertake research using the resources above independently and with partners to enhance the provision of advice to support longer-term improvement of public health.
Work with international partners such as the OECD to develop regulatory methods and guidance.

The Experimental Toxicology Team will also coordinate and drive forward our vision to ensure that the UKHSA maintains an enterprise level service supporting advice provision and business development.

Role Criteria and Other Requirements

Essential role criteria (including qualifications, licenses and registrations):

Higher Degree (MSc, MRes) in relevant subject (Toxicology, Biochemistry, Pharmacology, Chemistry, Biology or Physics) or equivalent related experience in subject area.
Postgraduate qualification (PhD/MD/DPhil level) in relevant subject (Toxicology, Biochemistry, Pharmacology, Chemistry, Biology or Physics) or equivalent experience of working at a similar level in a relevant specialist area.
Significant and relevant experience in toxicology, including molecular methods.
Experience managing specialist scientists working across academia, government and public and private sector settings.
Experience with advanced NAM toxicological methods for hazard assessment and the associated data analysis.
Experience of leading, motivating and managing a specialist team of scientific staff.
Ability to develop, inform and communicate toxicological data and other types of complex information for multiple level audiences in various settings.
Understanding of the role of chemical tests within a regulatory context and their development and validation and the role of national bodies and the OECD.
Understanding and experience of funding application principles and process accreditation.
An understanding of and commitment to equality of opportunity and good working relationships.

Desirable role criteria:

ERT (European Register of Toxicologists) Registered
Extensive peer reviewed academic/scientific publication record.

Selection Process Details

This vacancy will be assessed using a competency-based framework which will assess your qualifications, knowledge and experience and / or skills and abilities outlined in the essential criteria.

Stage 1: Application & Sift

You will be required to complete an application form. You will be assessed on the listed essential criteria, and this will be in the form of:

Application form (‘Employer/ Activity history’ section on the application)

Up to 1,000 words word supporting statement

Healthjobs UK has a word limit of 1500, but your supporting statement must be no more than 1,000 words.

This should outline how you consider your skills, experience, and knowledge, provide evidence of your suitability for the role, with reference to the essential criteria.

Please note you will not be able to upload your CV. You must complete the application form in as much detail as possible. Please do not email us your CV.

The Application form and supporting statement will be marked together.

Longlisting

In the event of a large number of applications we will longlist into 3 piles of:

Meets all essential criteria
Meets some essential criteria
Meets no essential criteria

The following will be taken through the next stage: Meets all essential criteria

Shortlisting

In the event of a large number of applications we will shortlist on:

Higher Degree (MSc, MRes) in relevant subject (e.g. Toxicology, Biochemistry, Pharmacology, Chemistry, Biology
or Physics) or equivalent related experience in subject area.
Postgraduate qualification (PhD/MD/DPhil level) in relevant subject (e.g. Toxicology, Biochemistry, Pharmacology, Chemistry, Biology
or Physics) or equivalent experience of working at a similar level in relevant specialist area.

If you are successful at this stage, you will progress to interview & assessment

Please do not exceed 1,000 words. We will not consider any words over and above this number.

Feedback will not be provided at this stage.

Stage 2: Interview (competency based)

You will be invited to a (single) face to face interview. If face to face interviews are planned, in exceptional circumstances, we may be able to offer a remote interview.

Knowledge, Experience, Skills & abilities and desirable criteria will be tested at interview.

You will be asked to deliver a 5–10-minute presentation aimed to assess your technical skills in regard to the following essential criteria:

Experience in Toxicology
Leading and managing scientists
Communication of complex information to multiple audiences

The question/subject of the presentation will be sent to successful candidates at interview stage.

Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.

Eligibility Criteria - External

Open to all external applicants (anyone) from outside the Civil Service (including by definition internal applicants).  

Location

This role is being offered as hybrid working based at our lab in Chilton (Didcot - Oxford). We offer great flexible working opportunities at UKHSA and operate using a hybrid working model where business needs allow. This provides us with greater flexibility about how and where we work, to get the best from our workforce. As a hybrid worker, you will be expected to spend a minimum of 60% of your contractual working hours (approximately 3 days a week pro rata, (averaged over a month).

If based at one of our labs, you will be required to have a minimum of a Counter Terrorism vetting security check as a minimum. For meaningful National Security Vetting checks to be carried out individuals need to have lived in the UK for a sufficient period of time. You should normally have been resident in the United Kingdom for the last 3 years as the role requires Counter Terrorism Check (CTC) clearance. In exceptional circumstances UK residency less than the outlined periods may not necessarily bar you from gaining national security vetting and applicants should contact the Vacancy Holder/Recruiting Manager listed in the advert for further advice.

Security Clearance Level Requirement 

All successful candidates must meet the basic security requirements before they can be appointed. The level of security needed is:

Basic Personnel Security Standard (BPSS).
Counter Terrorism Check (CTC)

DBS Requirement:

Basic DBS

Salary Information

If you are successful at interview, and are moving from another government department, NHS, or Local Authority, the relevant starting salary principles for level transfers or promotions will apply. Otherwise, roles are offered at the pay scale minimum for the grade, but in exceptional circumstances there may be flexibility if you are able to demonstrate you are already in receipt of an existing, higher salary. Pay increases are through the relevant annual pay award for the role and terms.

IMPORTANT - PLEASE READ

Artificial Intelligence (AI)

Artificial Intelligence can be a useful tool to support your application, however, all examples and statements provided must be truthful, factually accurate and taken directly from your own experience. Where plagiarism has been identified (presenting the ideas and experiences of others, or generated by artificial intelligence, as your own) applications may be withdrawn and internal candidates may be subject to disciplinary action. Please see our candidate guidance for more information on appropriate and inappropriate use.

Link below:

Artificial intelligence and recruitment | Civil Service Careers

This is a Non-Reserved post under the Civil Service Nationality Rules. To be eligible for employment in the UK Civil Service applicants must meet the Civil Service Nationality Rules (CSNRs) which operate independently of and additionally to the Immigration Rules. Applicants must also meet necessary security and vetting requirements, along with any other relevant pre-employment checks.

This job is broadly open to the following groups:

UK nationals
nationals of the Republic of Ireland
nationals of Commonwealth countries who have the right to work in the UK
nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities with settled or pre-settled status under the European Union Settlement Scheme (EUSS) (opens in a new window)
nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities who have made a valid application for settled or pre-settled status under the European Union Settlement Scheme (EUSS)
individuals with limited leave to remain or indefinite leave to remain who were eligible to apply for EUSS on or before 31 December 2020
Turkish nationals, and certain family members of Turkish nationals, who have accrued the right to work in the Civil Service

For more information on job nationality requirements and the right to work in the UK, see the Civil Service Nationality rules (opens in a new window) and the UK Visas and Immigration rules (opens in a new window)

For posts on UKHSA Civil Service terms and conditions, new entrants to the Civil Service are expected to start on the minimum of the pay band. For existing Civil Servants and roles advertised across government, the rules of transfer apply, i.e., level transfers move on current salary or the pay range minimum, transfers on promotion move to new pay range minimum or receive a 10% increase. Either case is determined by whichever is the highest.

The Civil Service pay structure and progression is different from NHS Agenda for Change (AfC), most local authority pay grades and other systems that have annual pay increments. For further details, please refer to the Information Sheet- Starting Salaries & Benefits attachment.

For AfC or Medical/Dental posts, you must have the correct professional registration to be appointed. The pay will follow the AfC or Medical & Dental terms & conditions. You may be asked to provide evidence of previous service whilst we are conducting pre-employment checks to determine your starting salary.

For Temporary Appointments, if you are not currently a civil servant, you will take up the post on a Fixed Term appointment.  You may be able to take this role up as a Secondment. If you are an existing Civil Servant, based outside of the UKHSA, you will take up the post as a loan which you will need your department to agree. You cannot take the post up as a fixed term. If you are an existing UKHSA member of staff, you will take up the post as either a level transfer or a temporary promotion as per the UKHSA’s Pay policy. 

Given the nature of the work of the UKHSA, as a Category 1 responder under the Civil Contingencies Act, you may be required in an emergency, if deemed a necessity, to redeploy to another role at short notice. You may also be required to work at any other location, within reasonable travelling distance of your permanent home address, in line with the provisions set out in your contract of employment.

Late Applications will unfortunately not be considered.

Working for the Civil Service

The Civil Service Code (opens in a new window) sets out the standards of behaviour expected of civil servants.

We recruit by merit on the basis of fair and open competition, as outlined in the Civil Service Commission's recruitment principles (opens in a new window).

The Civil Service embraces diversity and promotes equality of opportunity. The law requires that selection for appointment to the Civil Service is on merit on the basis of fair and open competition, as outlined in the Civil Service Commission's Recruitment Principles.

If you feel your application has not been treated in accordance with the Recruitment Principles, and you wish to make a complaint, in the first instance, you should contact UKHSA Public Accountability Unit via  email:  [email protected] If you are not satisfied with the response you receive from the Department, you can contact the Civil Service Commission: Visit the Civil Service Commission website here.

Reserve List - If more than the required number of suitable candidates pass the interview criteria, you may be kept on a reserve list for 12 months subject to your agreement. You may be contacted, in merit-order, if similar roles with closely matching essential criteria become available and the department choose to appoint from a reserve list.

The panel will assess if candidates meet the requirement of the role first, using a specific benchmark system. If you are interviewed for the post and do not meet the required threshold for the specified grade, your application may be assessed against a similar, lower grade role and you may be offered the post should one be available.

Interview expenses will not be reimbursed.

UKHSA is required to check employment and/or education history covering three consecutive years. Please ensure you give details of at least two different referees, even if you were employed in one company for three years or more.

If you are offered a job, information will also be transferred into the national NHS Electronic Staff Records system. Please note, all communication regarding your application will be made via email, please ensure you check your junk/spam folders as emails are sometimes filtered there.

Any move to UKHSA from another employer will mean you can no longer access childcare vouchers. This includes moves between government departments. You may however be eligible for other government schemes, including Tax-Free Childcare. Determine your eligibility at https://www.childcarechoices.gov.uk/.

 Benefits of working at UKHSA include:

Generous annual leave:
-26 days for the first 5 years of continuous service
-28 days after 5 years of continuous service
-32 days after 10 years of continuous service
-Plus public holidays and one privilege day for the King’s birthday
Access to a generous Defined Benefit pension scheme with employer contributions.
Access to a cycle-to-work salary sacrifice scheme, season ticket advances and payroll giving.
Access to a retail discounts and cashback site.
We also promote flexible working patterns (part-time, job-share, condensed hours). UKHSA views flexible working as essential in enabling us to recruit and retain talented people, ensuring that they are able to enjoy a long-lasting career with us. All employees have the right to apply for flexible working and there are a range of options available including working from home, compressed hours and job sharing.
We also offer a generous maternity/ paternity and adoption leave package.

Hybrid Working

UKHSA operates a hybrid working model where business needs allow. This provides us with greater flexibility about how and where we work, to get the best from our workforce.

As a hybrid worker, you will usually spend a minimum of 60% of your contracted hours (averaged over a month) working at one of UKHSA's locations (approximately 3 days a week pro rata) and the rest of your time working from home.

Disability Confident Scheme

The Civil Service embraces diversity and promotes equal opportunities. As such, we run a Disability Confident Scheme for candidates with disabilities who meet the minimum selection criteria at sift to ensure these candidates are invited to interview.   If you wish to be included in this scheme please tick the box on your application form.

Reasonable Adjustments

The Civil Service is committed to making sure that our selection methods are fair to everyone.

To help you during the recruitment process, we will take into account any reasonable adjustments that could help you.

An adjustment is a change to the recruitment process or an adjustment at work.

This is separate to the Disability Confident Scheme.

If you need an adjustment to be made at any point during the recruitment process you should:

Contact the recruitment team in confidence as soon as possible to discuss your needs.

You can find out more information about reasonable adjustments across the Civil Service here: https://www.civil-service-careers.gov.uk/reasonable-adjustments/

International Police Check

If you have spent more than 6 months abroad over the last 3 years you may need an International Police Check. This would not necessarily have to be in a single block, and could be time accrued over that period.

Internal Fraud check

If successful for this role as one aspect of pre-employment screening, applicant’s personal details – name, national insurance number and date of birth - will be checked against the Cabinet Office Internal Fraud Hub and anyone included on the database will be refused employment unless they can show exceptional circumstances. Currently this is only for External candidates to the Civil Service.

Security Vetting

Please check the Security Clearance needed for the role and follow the link for more information:

https://www.gov.uk/government/publications/united-kingdom-security-vetting-clearance-levels/national-security-vetting-clearance-levels

Future location

UKHSA is investing in a new state-of-the-art National Biosecurity Centre in Harlow, Essex, which will eventually bring together teams currently based at Canary Wharf, Colindale and Porton Down. For more details, please see: Huge biosecurity centre investment to boost pandemic protection - GOV.UK.

The new facilities will start becoming operational in the mid-2030s, with full completion by 2038. Staff will move in phases as facilities become available. If you're appointed to a role currently based at Canary Wharf, Colindale or Porton Down, please note that we'll continue investing in these sites for the next decade. As we get closer to the transition, we'll provide full information about relocation support available to staff.

Person specification

Application Form & Supporting Statement

Meini prawf hanfodol

Application Form and Supporting Statement

Essential Criteria

Meini prawf hanfodol

Knowledge, Experience, Skills & Abilities

Presentation

Meini prawf hanfodol

Presentation

Documents

Further details / informal visits contact

Enw: Conny Agyei
Teitl y swydd: Resourcing Support Officer
Cyfeiriad ebost: [email protected]
Gwybodaeth i gefnogi eich cais: For information regarding the role please contact [email protected] [Robie Kamanyire - Deputy Director]