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Guy's and St Thomas' NHS Foundation Trust

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Contact
- Address
- Trust Offices
- St Thomas' Street
- London
- SE1 9RT
- Contact Number
- 020 7188 7188
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Clinical Scientist in Genomics
Accepting applications until: 27-Aug-2025 23:59
Vacancy status: Open
Accepting applications until: 27-Aug-2025 23:59
Key details
Location
- Site
- Royal Brompton Hospital
- Address
- Sydney Street
- Town
- London
- Postcode
- SW3 6NP
- Major / Minor Region
- London
Contract type & working pattern
- Contract
- Fixed term: 2 years (Full time, with some remote working if necessary)
- Hours
- 37.5 sessions per week (Full time with some remote working if necessary)
Salary
- Salary
- £56,276 - £63,176 per annum inc. H.C.A
- Salary period
- Yearly
- Grade
- (Band 7)
Specialty
- Main area
- Health Science Services: Clinical Scientist
Guy’s and St Thomas’ is among the UK’s busiest and most successful NHS foundation trusts. We provide a full range of hospital and community services for people in south London and as well as specialist care for patients from further afield including cancer, renal, orthopaedic, respiratory and cardiovascular services.
Guy’s is home to the largest dental school in Europe and a £160 million Cancer Centre opened in 2016. As part of our commitment to provide care closer to home, in 2017 we also opened a cancer centre and a kidney treatment centre at Queen Mary’s Hospital in Sidcup. St Thomas’ has one of the largest critical care units in the UK and one of the busiest emergency departments in London. It is also home to Evelina London Children’s Hospital.
Evelina London cares for local children in Lambeth and Southwark and provides specialist services across south east England including cardiac, renal and critical care services. We lead a number of specialist service networks aiming to ensure children are treated locally where possible, but have access to specialist expertise when they need it. Our community services include health visiting, school nursing and support for families of children with long-term conditions.
Our adult community services teams deliver care at the heart of the local communities we serve, working in partnership with GPs, local authorities and other healthcare and voluntary sector organisations. Working with our partners in Lambeth and Southwark, we are focusing on new ways of working to improve care for local patients.
In February 2021 the Royal Brompton and Harefield joined Guy’s and St Thomas’ NHS Foundation Trust, bringing together world-leading expertise in the care and research of heart and lung disease. Our merger provides a once in a generation opportunity to build a lasting, world-renowned heart and lung centre, providing the highest quality care for patients and conducting world-leading research.
We have a reputation for clinical excellence and high quality teaching and research. We are part of King’s Health Partners, one of eight accredited UK academic health sciences centres. In partnership with King’s College London we have dedicated clinical research facilities including an MHRA accredited Phase I clinical trials unit.
Patients are at the heart of everything we do and we pride ourselves on ensuring the best possible patient experience as well as safe, high quality care. We are proud to have one of the lowest mortality rates in the NHS. Following a comprehensive Care Quality Commission (CQC) inspection in 2019 we maintained our overall rating of ‘good’. Our adult community services achieved a rating of ‘outstanding’.
The commitment of our 23,500 staff is key to our success. We are one of the largest local employers and we aim to develop and support all our staff so they are able to deliver high quality, safe and efficient care. The 2019 NHS staff survey results show that we have one of the most engaged and motivated workforces in the NHS. We know this has a positive impact on the care provided to our patients.
We have one of the most ambitious capital investment programmes anywhere in the NHS.
Job overview
An exciting opportunity has arisen to work within the Clinical Genetics & Genomics Laboratory (CGGL), based at the Royal Brompton Hospital, part of Guy’s and St Thomas’ NHS Foundation Trust. The Royal Brompton & Harefield NHS hospitals are the largest heart and lung centres in the UK and among the largest in Europe. We are a partnership of two specialist hospitals which are known throughout the world for our expertise, standard of care and research success.
The CGGL is a genomics diagnostic lab, providing state-of-the-art specialist cardiac and respiratory NGS-based genetic testing as part of the London South Genomics Laboratory Hub (LS GLH).
We are looking for a motivated Clinical Scientist, with extensive experience in human molecular genetic diagnostics, with excellent interpersonal skills, to join our group. The successful candidate will have the ability to critically analyse and interpret scientific data, and compile comprehensive, integrated genomic reports.
Applicants should have good computing skills, be capable of working under pressure, and be able to work collaboratively within a multidisciplinary team. They should have good organisational skills, be able to work methodically with great attention to detail and have a strong interest in driving and improving the quality of diagnostic services.
The CGGL is a UKAS-accredited medical laboratory, currently performing over 6000 diagnostic tests per annum and is also actively involved in research and teaching.
Advert
Provide senior laboratory staff with assistance relating to quality issues.
Present research and audit reports at local, regional and national scientific and clinical meetings
Be a member of Laboratory Medicine H&S committee and ensure health & safety information & requirements are communicated and actioned as required
Provide interpretation of the results of highly complex diagnostic investigations
Identify when techniques related to the processing of specimens are not working optimally
Provide a high level of expertise in molecular analysis for detection of genetic disease/abnormalities and in the interpretation of complex test results using international guidelines
Prepare and check standard & complex abnormal reports for authorisation by senior Clinical Scientists
Participate in internal & external quality control procedures
Assist during UKAS accreditation visits.
Perform the role following documented laboratory protocols
Assist in teaching genetics to medical, nursing & other clinical staff
Be familiar with the laboratory information management systems
Conduct data entry and analysis ensuring the validity & reliability of data at all times.
Undertake appropriate research & development of analytical procedures
Represent the Trust at regional & national conferences and on working groups as appropriate
Participate in internal research seminars/meetings including journal club
Maintain a portfolio of professional achievements
Participate in annual performance review
Working for our organisation
The Royal Brompton & Harefield Hospitals are part of Guy’s & St. Thomas’ NHS Foundation Trust, with the Heart and Lung Clinical Care Group forming the largest heart & lung centre in the UK & among the largest in Europe. We are a partnership of specialist hospitals which are known throughout the world for our expertise, standard of care and research success. The Clinical Genetics and Genomics Laboratory is also part of the NHSE South East Genomic Laboratory hub and is one of four cardiac and one of three respiratory laboratories, delivering the specialist testing nationally.
The Clinical Genetics & Genomics Laboratory in the Royal Brompton has generated deep expertise in cardiovascular (CV) and respiratory genetics through a large programme of work over the last 7 years and has established infrastructure, expertise and variant repositories on site. The CGGL has developed sophisticated bioinformatic tools and pipelines for the analysis and reporting of different types of sequence data and is actively involved in research to develop new technologies. The diagnostic service collaborates closely with the National Heart and Lung Institute (NHLI), Imperial College London.
Our values help us to define and develop our culture, what we do & how we do it. Our framework| describes what it means for every one of us in the Trust to put our values into action.
Detailed job description and main responsibilities
In conjunction with senior laboratory staff, the post-holder will undertake the scientific duties and responsibilities of a clinical scientist in the provision of a comprehensive, modern, high quality diagnostic clinical genetics service at RBHT. This will involve delivering a range of specialist molecular diagnostic tests for the diagnosis of inherited cardiovascular and respiratory diseases. The post holder will be expected to draft and authorize molecular genetic diagnostic reports in line with the services provided by the department. The post holder will also provide clinical and scientific advice to other health professionals including senior medical staff, on the selection, performance and interpretation of highly complex molecular genetic investigations. The post holder will participate in research and development and clinical audit where necessary.
Guy’s and St Thomas’ celebrates, respects and values the diversity of its staff and patients. We review our policies, procedures and practices to ensure that all employees, patients and carers are treated equitable according to their needs. We are actively committed to ensuring that no one who applies for a job, works or study’s at the Trust, or accesses our services is discriminated against on the grounds of race, ethnicity, nationality, disability, religion or belief, age, gender identity , gender reassignment, sexual orientation, pregnancy and maternity/paternity, or marital/civil partnership.
Applications are welcomed from applicants with a disability. We can make reasonable adjustments and offer support and advice in a variety of ways throughout the application process. Equality of opportunity is our policy.
As an organisation we are committed to developing our services in ways that best suit the needs of our patients. This means that some staff groups will increasingly be asked to work a more flexible shift pattern so that we can offer services in the evenings or at weekends.
Flexible working
We are committed to supporting all employees to achieve a healthy work life balance and to work in a way that is best for them and our patients. We will consider all requests to work flexibly, taking in to account the individual’s personal circumstances as well the needs of the service. We encourage all prospective applicants to discuss their individual circumstances with the recruiting manager as part of the on-boarding process.
Your e-mail address is important to us - We communicate to all job applicants via the e-mail address which has been provided on the application form. Please ensure that you check your e-mail on a regular basis.
Please apply for this post by clicking "Apply Online Now."
Applicant requirements
Person specification
Qualifications / Education
Essential criteria
- Educated to MSc, or equivalent in genome biology, bioinformatics or computer sciences
- PhD or equivalent in genome biology, bioinformatics or computer science.
Desirable criteria
- Membership of a professional body Health Professions Council registered Clinical Scientist in Genomics or equivalent international qualification.
Professional/ Statutory Registration
Essential criteria
- Registered with the HCPC as a Clinical Scientist
Previous Experience & Knowledge
Essential criteria
- Experience in diagnostic genetic testing using DNA sequencing including Next-Generation sequencing (NGS), DNA fragment analysis and other DNA-based techniques.
- Knowledge of laboratory accreditation requirements (UKAS) according to ISO15189
- Good computer skills and knowledge of relevant molecular genetic databases. An understanding of genome annotation and the use of web-based browsers to interrogate genomic information
- Knowledge of health and safety legislation as it relates to a specialist genetic laboratory and general laboratory medicine.
- Knowledge of the genetic basis of human disease
Desirable criteria
- Experience of generating and participating in collaborative research projects.
- Experience of research in a clinical environment.
- Proven publication record in peer-review journals.
SKILLS & ABILITIES
Essential criteria
- The ability to develop effective working relationships with all levels of administrative and academic staff, and students
- Excellent organisational, communication and interpersonal skills
- Effective analytical, decision-making and problem-solving capability
- The ability to prioritise workload
- The ability to work under pressure and to manage multiple tasks simultaneously, successfully meeting deadlines
- Ability to work under pressure and to manage multiple tasks simultaneously, successfully meeting deadlines
- An open and positive attitude to working in a changing environmen
- Clear, concise report writing skills
- A high degree of tact, diplomacy and confidentiality
- The ability swiftly to assimilate and synthesise new information
PERSONAL QUALITIES
Essential criteria
- Innovative and proactive approach with a willingness to accept responsibility for management decisions
- Meticulous approach and attention to detail
- Willingness to work as part of a team and to be openminded and co-operative
- Flexible attitude towards working hours.
- Discipline and regard for confidentiality, safety and security at all times.
- Willingness to train others and undertake training, as appropriate.
Further details / informal visits contact
- Name
- Matthew Edwards
- Job title
- Deputy Head of Clinical Genetics & Genomics Lab
- Email address
- [email protected]
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