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UK Health Security Agency
About
The UK Health Security Agency (UKHSA) will be responsible for planning, preventing and responding to external health threats, and providing intellectual, scientific and operational leadership at national and local level, as well as on the global stage. UKHSA will ensure the nation can respond quickly and at greater scale to deal with pandemics and future threats.
Contact
- Address
- 10 South Colonnade
- London
- E14 4PU
Unit Head of Colindale Sequencing Laboratory (CSL)
Accepting applications until: 17-Dec-2025 23:59
Vacancy status: Open
Accepting applications until: 17-Dec-2025 23:59
Key details
Location
- Site
- Colindale
- Town
- Colindale, London
- Postcode
- NW9 5EQ
- Major / Minor Region
- London
Contract type & working pattern
- Contract
- Permanent
- Hours
- Full time
- Part time
- Job share
- Flexible working
Salary
- Salary
- £76,965 - £88,682 per annum, pro rata. Plus, Outer HCAS. Up to 15% of basic salary PA PR
- Salary period
- Yearly
- Grade
- (NHS AfC: Band 8c)
Specialty
- Main area
- Science
The United Kingdom Health Security Agency (UKHSA) is a system leader for health security; taking action internationally to strengthen global health security, providing trusted advice to government and the public and reducing inequalities in the way different communities experience and are impacted by infectious disease, environmental hazards, and other threats to health.
UKHSA’s remit, as an agency with a global-to-local reach, is to protect the health of the nation from infectious diseases and other external threats to health. As the nation’s expert national health security agency UKHSA will:
- Prevent: anticipate threats to health and help build the nation’s readiness, defences and health security
- Detect: use cutting edge environmental and biological surveillance to proactively detect and monitor infectious diseases and threats to health
- Analyse: use world-class science and data analytics to assess and continually monitor threats to health, identifying how best to control and mitigate the risks
- Respond: take rapid, collaborative and effective actions nationally and locally to mitigate threats to health when they materialise
- Lead: lead strong and sustainable global, national, regional and local partnerships designed to save lives, protect the nation from public health threats and reduce inequalities.
Job overview
The Colindale Sequencing Laboratory (CSL) provides a variety of nucleic acid sequencing services using Next Generation Sequencing (NGS) and Sanger technology to sequence genomic DNA, PCR amplicons, or short DNA fragments, as well as providing DNA-based fragment analysis to size fluorescently labelled PCR products. For Sanger sequencing and fragment analysis, the unit receives nucleic acid, plasmids and PCR products from UKHSA and external customers. CSL also offers various levels of NGS for genomic DNA (usually bacterial DNA extracts) and PCR amplicons (usually generated from viral samples) to service users. NGS is currently performed using Illumina or Oxford Nanopore Technology (ONT) on the NextSeq, MiSeq or GridION. Sequence and fragment analysis data are checked by CSL staff against internal standards and quality scores before electronically notifying and reporting the results to our customers, who analyse their own data.
CSL has a strong service delivery focus and commitment to continuously improving methods for rapid and high throughput genomics to enhance its function.
The Unit Head of the CSL is responsible for leading and managing the routine provision, delivery and development of genomic services for customers of CSL, and acts as the senior specialist for NGS and Sanger services. The post holder will be accountable for scientists within the unit, providing leadership and oversight for the day-to-today running and development of the NGS and Sanger services.
Advert
- Responsible for provision of expert scientific leadership, the strategic development and operational service delivery of the CSL.
- To advise Public Health Microbiology (PHM) Laboratories and UKHSA on best practice in laboratory sequencing.
- To manage the provision of an efficient, effective and timely service, ensuring maximum productivity within allocated resources/budgets and within agreed performance standards.
- To ensure the CSL offers genomic services under a Quality Management System in accordance with UKHSA policies, and Quality standards set by external accreditation bodies (e.g. UKAS).
- To be accountable for Health and Safety within the CSL.
- To ensure that the CSL delivers and develops services and provides expert advice for wider public health delivery, and also provides national and international specialist services and advice to customers.
- Provide leadership to ensure services contribute to the national development of genomics-based PHM delivery.
- Contribute to test development and validation.
- Review platform use and manage implementation of new equipment to support service delivery improvement.
- To maintain and further develop the national and international reputation of the CSL through development of strategic academic, public sector and other partnerships including funding application, participation, design, implementation and overall management of appropriate R&D projects.
Working for our organisation
We pride ourselves as being an employer of choice, where Everyone Matters promoting equality of opportunity to actively encourage applications from everyone, including groups currently underrepresented in our workforce. UKHSA ethos is to be an inclusive organisation for all our staff and stakeholders. To create, nurture and sustain an inclusive culture, where differences drive innovative solutions to meet the needs of our workforce and wider communities. We do this through celebrating and protecting differences by removing barriers and promoting equity and equality of opportunity for all. Please visit our careers site for more information https://gov.uk/ukhsa/careers
Detailed job description and main responsibilities
- In partnership with PHM Laboratories staff, develop strong integration between nucleic acid extraction and upstream sample processing.
- Maintain strong linkages with the processing and analysis of sequence data.
Detailed job description and main responsibilities
- To be responsible for the provision of expert advice and CSL services for clinically significant organisms, including the provision of interpretation of data for laboratory reports with expert comment and advice to Consultant Medical Microbiologists, Consultants in Health Protection, Senior Officers of the Department of Health and Social Care and other Government bodies and international Institutes.
- Work collaboratively with UKHSA and NHS laboratories and other Government bodies, Academic and international Institutes and provide support, leadership and strategy for the implementation and development of molecular technologies for Clinical PHM (supporting UKHSA, NHS and Academic and other institutes).
- On behalf of UKHSA provide expert scientific, professional and managerial inputs for the activities of Working Groups and Specialist committees in pathogen laboratory sequencing.
- To be responsible for the management, health and safety and training of CSL staff, visitors, trainees and PhD students.
- To maintain an awareness of Health and Safety and comply with current site requirement and ensure that relevant legislations and policies are implemented within CSL and ensure that it is compliant with statutory Health and Safety Regulations, including COSHH, together with the appropriate accreditation systems and that staff have appropriate registration and maintain participation with Continued Professional Development Schemes.
- To manage the CSL budget, including budget control, expenditure projections, equipment priorities, external funding and income generation activities.
- Manage the quality, performance and verification of the accredited CSL laboratory services ensuring compliance with UKAS standards.
- To assist in the operation of PHM Laboratories by membership of PHM Management Groups.
- To represent CSL and PHM laboratories at internal/external, local, national & international meetings and committees.
- To lead working groups and discussion on the strategic planning and implementation of UKHSA sequencing services.
- To contribute, manage and provide expertise and leadership to CSL business management including negotiation with customers, reviewing efficiency and Unit performance and pursuing business opportunities within UKHSA and with external customers.
- To be an on-call expert in laboratory sequencing of bio-threat agents.
This is not an exhaustive list.
Essential criteria
- Degree (BSc / MSc) in a biological science, molecular biology or bioinformatics.
- PhD in molecular microbiological subject or equivalent experience in relevant laboratory sciences
- Relevant professional qualification i.e., registration with the Health and Care Professions Council (HCPC) as Clinical Scientist or Biomedical Scientist
- Expertise in the areas covered by the unit and experience in running NGS Platforms and Applied Biosystems sequencing
- Proven and extensive experience of supervision and leadership
- Knowledge of automated liquid handling
- Experience, knowledge and understanding of Quality Assurance Principles and Procedures
- Experience, knowledge and understanding of laboratory safety requirements and procedures
- Experience in training staff and competency assessment
- Knowledge of clinical microbiology, including bacteriology and virology.
- Data analysis and data presentation skills: Presenting evaluation information to meetings/groups where highly qualified experts debate the work the post holder has prepared
- Skills for communication on complex information and administrative matters, requiring developed interpersonal and oral/ written communication skills
- Able to communicate effectively with all grades of staff both internal and external to the UKHSA
- Problem solving skills and ability to respond to sudden unexpected demands
- Advanced keyboard skills, use of a range of software
- Ability to work on own initiative and organise own workload with minimal supervision working to tight and often changing timescales
- An understanding of and commitment to equality of opportunity and good working relationships, both in terms of day-to-day working practices, but also in relation to management systems
Desirable criteria:
- Relevant business or management training to certificate level
- Experience and knowledge of project principles
- Evidenced management experience of at least five years for scientific, technical and student staff.
- R&D project management and team building experience
- Strong R&D publication record and presenting at national and international audience
- Ability to attract external and internal grant funding
- Excellent time management skills with the ability to re-prioritise
Selection Process Details:
This vacancy will be assessed using a competency-based framework which will assess your qualifications, knowledge and experience and / or skills and abilities outlined in the essential criteria.
Stage 1: Application & Sift
You will be required to complete an application form. You will be assessed on the listed 17 essential criteria, and this will be in the form of a:
- Application form (‘Employer/ Activity history’ section on the application)
- Up to 1,200 supporting statement
This should outline how your skills, experience, and knowledge, provide evidence of your suitability for the role, with reference to the essential criteria.
The Application form and supporting statement will be marked together.
Please note you will not be able to upload your CV. You must complete the application form in as much detail as possible. Please do not email us your CV.
Longlisting:
In the event of a large number of applications we will longlist into 3 piles of:
- Meets all essential criteria
- Meets some essential criteria
- Meets no essential criteria
The following will be taken through to the next stage:
- Meets all essential criteria
- Meets some essential criteria
Shortlisting:
In the event of a large number of applications we will shortlist on the following:
- Degree (BSc / MSc) in a biological science, molecular biology or bioinformatics.
- PhD in molecular microbiological subject or equivalent experience in relevant laboratory sciences
- Relevant professional qualification i.e., registration with the Health and Care Professions Council (HCPC) as Clinical Scientist or Biomedical Scientist
- Expertise in the areas covered by the unit and experience in running NGS Platforms and Applied Biosystems sequencing
- Proven and extensive experience of supervision and leadership
Desirable criteria may be used in the event of a large number of applications / large amount of successful candidates.
If you are successful at this stage, you will progress to interview & assessment.
Please do not exceed 1,200 words. We will not consider any words over and above this number.
Feedback will not be provided at this stage.
Stage 2: Interview (competency based)
You will be invited to a (single) face to face interview at Colindale. In exceptional circumstances, we may be able to offer a remote interview via teams.
Knowledge, experience, skills & abilities will be tested at interview
You will be asked to prepare and present a 10-minute presentation at the start of your interview. The presentation will be designed to allow the candidates to demonstrate their knowledge of and experience in leading and delivering a Next Generation Sequencing service. Full details will be provided at interview stage.
Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.
Location
This role is being offered as hybrid working based at our Scientific Campus in Colindale.
We offer great flexible working opportunities at UKHSA and operate using a hybrid working model where business needs allow. This provides us with greater flexibility about how and where we work, to get the best from our workforce. As a hybrid worker, you will be expected to spend a minimum of 60% of your contractual working hours (approximately 3 days a week pro rata, (averaged over a month).
If based at one of our scientific campuses, you will be required to have a minimum of a Counter Terrorism Check security vetting check as a minimum. For meaningful National Security Vetting checks to be carried out individuals need to have lived in the UK for a sufficient period of time. You should normally have been resident in the United Kingdom for the last 3 years as the role requires Counter Terrorism Check (CTC) clearance. In exceptional circumstances UK residency less than the outlined periods may not necessarily bar you from gaining national security vetting and applicants should contact the Vacancy Holder/Recruiting Manager listed in the advert for further advice.
Security Clearance Level Requirement
Successful candidates must pass a disclosure and barring security check.
Successful candidates must meet the security requirements before they can be appointed. The level of security needed is Counter-terrorist Check.
Eligibility Criteria – External
Open to all external applicants (anyone) from outside the Civil Service (including internal applicants).
Salary Information
If you are successful at interview, and are moving from another government department, NHS, or Local Authority, the relevant starting salary principles for level transfers or promotions will apply. Otherwise, roles are offered at the pay scale minimum for the grade, but in exceptional circumstances there may be flexibility if you are able to demonstrate you are already in receipt of an existing, higher salary. Pay increases are through the relevant annual pay award for the role and terms.
IMPORTANT - PLEASE READ
Artificial Intelligence (AI)
Artificial Intelligence can be a useful tool to support your application, however, all examples and statements provided must be truthful, factually accurate and taken directly from your own experience. Where plagiarism has been identified (presenting the ideas and experiences of others, or generated by artificial intelligence, as your own) applications may be withdrawn and internal candidates may be subject to disciplinary action. Please see our candidate guidance for more information on appropriate and inappropriate use.
Link below:
Artificial intelligence and recruitment | Civil Service Careers
This is a Non-Reserved post under the Civil Service Nationality Rules. To be eligible for employment in the UK Civil Service applicants must meet the Civil Service Nationality Rules (CSNRs) which operate independently of and additionally to the Immigration Rules. Applicants must also meet necessary security and vetting requirements, along with any other relevant pre-employment checks.
This job is broadly open to the following groups:
- UK nationals
- nationals of the Republic of Ireland
- nationals of Commonwealth countries who have the right to work in the UK
- nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities with settled or pre-settled status under the European Union Settlement Scheme (EUSS) (opens in a new window)
- nationals of the EU, Switzerland, Norway, Iceland or Liechtenstein and family members of those nationalities who have made a valid application for settled or pre-settled status under the European Union Settlement Scheme (EUSS)
- individuals with limited leave to remain or indefinite leave to remain who were eligible to apply for EUSS on or before 31 December 2020
- Turkish nationals, and certain family members of Turkish nationals, who have accrued the right to work in the Civil Service
For more information on job nationality requirements and the right to work in the UK, see the Civil Service Nationality rules (opens in a new window) and the UK Visas and Immigration rules (opens in a new window)
For posts on UKHSA Civil Service terms and conditions, new entrants to the Civil Service are expected to start on the minimum of the pay band. For existing Civil Servants and roles advertised across government, the rules of transfer apply, i.e., level transfers move on current salary or the pay range minimum, transfers on promotion move to new pay range minimum or receive a 10% increase. Either case is determined by whichever is the highest.
The Civil Service pay structure and progression is different from NHS Agenda for Change (AfC), most local authority pay grades and other systems that have annual pay increments. For further details, please refer to the Information Sheet- Starting Salaries & Benefits attachment.
For AfC or Medical/Dental posts, you must have the correct professional registration to be appointed. The pay will follow the AfC or Medical & Dental terms & conditions. You may be asked to provide evidence of previous service whilst we are conducting pre-employment checks to determine your starting salary.
For Temporary Appointments, if you are not currently a civil servant, you will take up the post on a Fixed Term appointment. You may be able to take this role up as a Secondment. If you are an existing Civil Servant, based outside of the UKHSA, you will take up the post as a loan which you will need your department to agree. You cannot take the post up as a fixed term. If you are an existing UKHSA member of staff, you will take up the post as either a level transfer or a temporary promotion as per the UKHSA’s Pay policy.
Given the nature of the work of the UKHSA, as a Category 1 responder under the Civil Contingencies Act, you may be required in an emergency, if deemed a necessity, to redeploy to another role at short notice. You may also be required to work at any other location, within reasonable travelling distance of your permanent home address, in line with the provisions set out in your contract of employment.
Late Applications will unfortunately not be considered.
Working for the Civil Service
We recruit by merit on the basis of fair and open competition, as outlined in the Civil Service Commission's recruitment principles (opens in a new window).
The Civil Service embraces diversity and promotes equality of opportunity. The law requires that selection for appointment to the Civil Service is on merit on the basis of fair and open competition, as outlined in the Civil Service Commission's Recruitment Principles.
If you feel your application has not been treated in accordance with the Recruitment Principles, and you wish to make a complaint, in the first instance, you should contact UKHSA Public Accountability Unit via email: [email protected] If you are not satisfied with the response you receive from the Department, you can contact the Civil Service Commission: Visit the Civil Service Commission website here.
Reserve List - If more than the required number of suitable candidates pass the interview criteria, you may be kept on a reserve list for 12 months subject to your agreement. You may be contacted, in merit-order, if similar roles with closely matching essential criteria become available and the department choose to appoint from a reserve list.
The panel will assess if candidates meet the requirement of the role first, using a specific benchmark system. If you are interviewed for the post and do not meet the required threshold for the specified grade, your application may be assessed against a similar, lower grade role and you may be offered the post should one be available.
Interview expenses will not be reimbursed.
UKHSA is required to check employment and/or education history covering three consecutive years. Please ensure you give details of at least two different referees, even if you were employed in one company for three years or more.
If you are offered a job, information will also be transferred into the national NHS Electronic Staff Records system. Please note, all communication regarding your application will be made via email, please ensure you check your junk/spam folders as emails are sometimes filtered there.
Any move to UKHSA from another employer will mean you can no longer access childcare vouchers. This includes moves between government departments. You may however be eligible for other government schemes, including Tax-Free Childcare. Determine your eligibility at https://www.childcarechoices.gov.uk/.
Benefits of working at UKHSA include:
- Generous annual leave:
-26 days for the first 5 years of continuous service
-28 days after 5 years of continuous service
-32 days after 10 years of continuous service
-Plus public holidays and one privilege day for the King’s birthday - Access to a generous Defined Benefit pension scheme with employer contributions.
- Access to a cycle-to-work salary sacrifice scheme, season ticket advances and payroll giving.
- Access to a retail discounts and cashback site.
- We also promote flexible working patterns (part-time, job-share, condensed hours). UKHSA views flexible working as essential in enabling us to recruit and retain talented people, ensuring that they are able to enjoy a long-lasting career with us. All employees have the right to apply for flexible working and there are a range of options available including working from home, compressed hours and job sharing.
- We also offer a generous maternity/ paternity and adoption leave package.
Hybrid Working
UKHSA operates a hybrid working model where business needs allow. This provides us with greater flexibility about how and where we work, to get the best from our workforce.
As a hybrid worker, you will usually spend a minimum of 60% of your contracted hours (averaged over a month) working at one of UKHSA's locations (approximately 3 days a week pro rata) and the rest of your time working from home.
Disability Confident Scheme
The Civil Service embraces diversity and promotes equal opportunities. As such, we run a Disability Confident Scheme for candidates with disabilities who meet the minimum selection criteria at sift to ensure these candidates are invited to interview. If you wish to be included in this scheme please tick the box on your application form.
Reasonable Adjustments
The Civil Service is committed to making sure that our selection methods are fair to everyone.
To help you during the recruitment process, we will take into account any reasonable adjustments that could help you.
An adjustment is a change to the recruitment process or an adjustment at work.
This is separate to the Disability Confident Scheme.
If you need an adjustment to be made at any point during the recruitment process you should:
Contact the recruitment team in confidence as soon as possible to discuss your needs.
You can find out more information about reasonable adjustments across the Civil Service here: https://www.civil-service-careers.gov.uk/reasonable-adjustments/
International Police Check
If you have spent more than 6 months abroad over the last 3 years you may need an International Police Check. This would not necessarily have to be in a single block, and could be time accrued over that period.
Internal Fraud check
If successful for this role as one aspect of pre-employment screening, applicant’s personal details – name, national insurance number and date of birth - will be checked against the Cabinet Office Internal Fraud Hub and anyone included on the database will be refused employment unless they can show exceptional circumstances. Currently this is only for External candidates to the Civil Service.
Security Vetting
Please check the Security Clearance needed for the role and follow the link for more information:
https://www.gov.uk/government/publications/united-kingdom-security-vetting-clearance-levels/national-security-vetting-clearance-levels
Future location
UKHSA is investing in a new state-of-the-art National Biosecurity Centre in Harlow, Essex, which will eventually bring together teams currently based at Canary Wharf, Colindale and Porton Down. For more details, please see: Huge biosecurity centre investment to boost pandemic protection - GOV.UK.
The new facilities will start becoming operational in the mid-2030s, with full completion by 2038. Staff will move in phases as facilities become available. If you're appointed to a role currently based at Canary Wharf, Colindale or Porton Down, please note that we'll continue investing in these sites for the next decade. As we get closer to the transition, we'll provide full information about relocation support available to staff.
Applicant requirements
Person specification
Application form and supporting statement
Essential criteria
- Application form and supporting statement
Essential Criteria
Essential criteria
- Questions on experience, knowledge and skills
Essential Criteria
Essential criteria
- Presentation
Documents
- Job Advert (PDF, 312.3KB)
- Civil Service Recruitment Principles (PDF, 2.6MB)
- Civil Service Nationality Rules (PDF, 195.3KB)
- Application Form Guidance Notes (PDF, 77.3KB)
- Information Sheet - Starting salaries and benefits (PDF, 129.4KB)
- Information Sheet - Selection Process (PDF, 110.1KB)
- Working at UKHSA and your benefits (PDF, 219.2KB)
Further details / informal visits contact
- Name
- Gurkamal Bhambra
- Job title
- Resourcing
- Email address
- [email protected]
- Additional information
For information regarding the role please contact [email protected]
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