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University College London Hospitals NHS Foundation Trust
About
Contact
- Address
- Trust Headquarters
- 250 Euston Road
- London
- NW1 2PG
- Contact Number
- 0845 1555 000
Find out more
open_in_new JobsPost-doctoral Scientist
Accepting applications until: 06-Apr-2026 23:59
Vacancy status: Open
Accepting applications until: 06-Apr-2026 23:59
Key details
Location
- Site
- University College London Hospital
- Address
- 235 Euston Road
- Town
- London
- Postcode
- NW1 2BU
- Major / Minor Region
- London
Contract type & working pattern
- Contract
- Fixed term: 18 months (due to limited funding)
- Hours
- Full time - 37.5 hours per week
Salary
- Salary
- £46,419 - £55,046 per annum inclusive of HCAS
- Salary period
- Yearly
- Grade
- (NHS AfC: Band 6)
Specialty
- Main area
- Dermatology
The use of AI is monitored and if applicants have used it, then they are required to declare this in their supporting statement.
Artificial intelligence (AI) is a set of technology that can perform various tasks that typically required human intelligence. Your application is your opportunity to demonstrate to us how you meet the requirements of the role.
We recognise that AI tools can support accessibility, equity and confidence for applicants. However, it’s important that examples and responses genuinely reflect your own experience and abilities, as these will be explored further during the selection process. AI must not be used to provide misleading or false information during any stage of the application journey.
Further guidance can be found in the NLPSS Applicant Toolkit https://royalfree.pagetiger.com/cuuomnr/1.
University College London Hospitals NHS Foundation Trust is committed to fair and transparent recruitment and requires applicants to provide accurate information, as misleading details may affect their application or employment and may be verified in line with the Fraud Act 2006. For further information please visit https://royalfree.pagetiger.com/cuuomnr/1.
Job overview
UCLH Charities are funding the start-up of a pioneering ageing research centre within the Department of Ageing, Rheumatology and Regenerative Medicine, Division of Medicine, UCL. Dr Priya Subramanian, Consultant Dermatologist and Principal Investigator, leads the arm of human basic science research bridging dermatology, cancer biology and ageing, with a focus on how loss of p16, a key regulator of senescence, drives both tumour initiation and immune dysfunction
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The postholder will work alongside Dr Subramanian to deliver research aims and objectives detailed in a recently awarded British Skin Foundation (BSF) grant. This project aims to both understand disease-specific impacts of mutated p16, and mechanistically understand the impact of p16 on human senescence, with relevance to the fields of cancer biology, senescence and ageing research. We will characterise immune and senescence-associated changes in CDKN2A-mutated human melanocytes and T cells using a unique, well-phenotyped biobank of skin and blood samples. We will apply multiplexed histology, high-parameter flow cytometry and in vitro co-culture models to: 1) define senescence and immune escape phenotypes of CDKN2A-mutated melanocytes under physiological and induced stress conditions; 2) identify alterations in circulating T cells that compromise melanoma immunosurveillance; and 3) test the cytotoxic capacity of autologous T cells against CDKN2A-mutated human melanocytes in vitro.
The post is for 18 months
Working for our organisation
University College London Hospitals NHS Foundation Trust (UCLH) is one of the most complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services, to people from the local area, from throughout the United Kingdom and overseas. Our vision is to deliver top-quality patient care, excellent education, and world-class research.
We provide first-class acute and specialist services across eight sites:
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University College Hospital (incorporating the Elizabeth Garrett Anderson Wing)
-
National Hospital for Neurology and Neurosurgery
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Royal National ENT and Eastman Dental Hospitals
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University College Hospital Grafton Way Building
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Royal London Hospital for Integrated Medicine
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University College Hospital Macmillan Cancer Centre
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The Hospital for Tropical Diseases
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University College Hospital at Westmoreland Street
We are dedicated to the diagnosis and treatment of many complex illnesses. UCLH specialises in women’s health and the treatment of cancer, infection, neurological, gastrointestinal and oral disease. It has world class support services including critical care, imaging, nuclear medicine and pathology.
We are committed to sustainability and have pledged to become a carbon net zero health service, embedding sustainable practice throughout UCLH. We have set an ambitious target of net zero for our direct emissions by 2031 and indirect emissions by 2040.
Detailed job description and main responsibilities
For the full Person Specification and more information regarding the main responsibilities of this role, please refer to the attached Job Description.
Come and be a part of the best NHS trust in England to work for, according to our staff*
* UCLH top trust to work at in England - In the most recent NHS staff survey UCLH had the highest percentage of staff who said they would recommend us as a place to work, out of all general acute or acute/community NHS trusts in England – for the third year in a row.
UCLH recognises the benefits of flexible working for staff – To find out more, visit: Flexible working.
To discover more about what makes UCLH a great place to work, visit: Why Choose UCLH?
At UCLH, we have a real ‘One Team’ ethos, and our values – safety, kindness, teamwork and improving, are central to the way we work. This is supported by our staff, who voted us as the #1 NHS Acute Trust to work for in the whole of England.
At UCLH we take equality of opportunity seriously and are committed to being a diverse and inclusive employer, with a culture that creates a real sense of belonging and trust. It is our fundamental aim, to recruit, retain and promote a diverse mix of people who are representative of our local communities. Applications are encouraged from candidates of all backgrounds, cultures, and perspectives to support our world class research, innovation and creativity.
UCLH recognises the benefits of flexible working for staff and has a dedicated policy which allows staff to apply for flexible working right from the beginning of employment. For more information please go to: https://www.uclh.nhs.uk/work-with-us/why-choose-uclh/flexible-working.
We offer our permanent staff an interest free season ticket loan for travel, all our staff have access to free independent and confidential support, large retail discounts, a staff discount platform, cycle to work scheme and on-site accommodation to name a few.
Additionally, UCLH Arts and Heritage’s staff wellbeing programme, Creative Comfort, offers a variety of ways to engage with the arts as a member of UCLH staff. You can try out the weekly choir, weekly art club and join the Culture Club for exclusive access to free and discounted tickets for opera, exhibitions, theatre and more.
We recognise, reward and thank colleagues by nominating them for our annual Celebrating Excellence Awards, which are funded by UCLH Charity.
We are also members of www.mytrustbenefits.co.uk/ which offers discounts on high street retail stores, offers on travel deals, and also to take advantage of cash back schemes.
This vacancy may close before the current listed closing date. You are advised not to delay submitting your completed application.
Please note that all correspondence regarding your application will be via email. The emails will be sent to you via TRAC.jobs and not via NHS Jobs, we encourage you to check your inbox regularly.
Please note that if you have not heard from us within 3 weeks of the closing date of the advert to assume that you have not been shortlisted on this occasion.
The Trust uses electronic new starter forms on Trac to collect personal details. Information collected is securely stored and used to set up the employee record on the ESR HR system.
Applicant requirements
Person specification
Knowledge and Qualifications
Essential criteria
- PhD in a relevant subject area
Experience
Essential criteria
- Previous experience of performing experiments with human samples
- Experience teaching and training staff and students
- Experience of preparing manuscripts for publications
Communication
Essential criteria
- Demonstrates awareness of the importance of working as part of a collaborative and multi-disciplinary team.
- Communicates effectively verbally, in writing and in electronic formats
- Able to effectively communicate experimental concepts, data and results verbally, in writing and in electronic formats
Skills and Abilities
Essential criteria
- Specific experimental skills in histology, flow cytometry, and cell culture
- Demonstrates ability to prioritise workload and work to deadlines
- Acts on own initiative and problem-solves utilising resources available
- Demonstrates understanding of laboratory-based health and safety principles
- Demonstrates understanding of budgetary management
- Self-motivated and enthusiastic individual
- High degree of flexibility and initiative; ability to ask for advice where needed
- Demonstrates evidence of professional and personal development
Desirable criteria
- Experimental skills in Western blot, cytometric bead array, and qPCR
- Bioinformatics analysis of datasets
Further details / informal visits contact
- Name
- Mhairi Irvine
- Job title
- General Manager
- Email address
- [email protected]
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