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Guy's and St Thomas' NHS Foundation Trust
About
Contact
- Address
- Trust Offices
- St Thomas' Street
- London
- SE1 9RT
- Contact Number
- 020 7188 7188
Senior Genomics Technician
Closed for applications on: 14-May-2026 00:01
Vacancy status: Closed
Closed for applications on: 14-May-2026 00:01
Key details
Location
- Site
- 10th Floor, Guy's Tower Wing
- Address
- 10th Floor, Guy's Tower Wing
- Town
- London
- Postcode
- SE1 9RT
- Major / Minor Region
- London
Contract type & working pattern
- Contract
- Permanent
- Hours
- Full time
Salary
- Salary
- £47,951 - £56,863 p.a. inc HCA
- Salary period
- Yearly
- Grade
- (NHS AfC: Band 6)
Specialty
- Main area
- Genomics
Guy’s and St Thomas’ is among the UK’s busiest and most successful NHS foundation trusts. We provide a full range of hospital and community services for people in south London and as well as specialist care for patients from further afield including cancer, renal, orthopaedic, respiratory and cardiovascular services.
Guy’s is home to the largest dental school in Europe and a £160 million Cancer Centre opened in 2016. As part of our commitment to provide care closer to home, in 2017 we also opened a cancer centre and a kidney treatment centre at Queen Mary’s Hospital in Sidcup. St Thomas’ has one of the largest critical care units in the UK and one of the busiest emergency departments in London. It is also home to Evelina London Children’s Hospital.
Evelina London cares for local children in Lambeth and Southwark and provides specialist services across south east England including cardiac, renal and critical care services. We lead a number of specialist service networks aiming to ensure children are treated locally where possible, but have access to specialist expertise when they need it. Our community services include health visiting, school nursing and support for families of children with long-term conditions.
Our adult community services teams deliver care at the heart of the local communities we serve, working in partnership with GPs, local authorities and other healthcare and voluntary sector organisations. Working with our partners in Lambeth and Southwark, we are focusing on new ways of working to improve care for local patients.
In February 2021 the Royal Brompton and Harefield joined Guy’s and St Thomas’ NHS Foundation Trust, bringing together world-leading expertise in the care and research of heart and lung disease. Our merger provides a once in a generation opportunity to build a lasting, world-renowned heart and lung centre, providing the highest quality care for patients and conducting world-leading research.
We have a reputation for clinical excellence and high quality teaching and research. We are part of King’s Health Partners, one of eight accredited UK academic health sciences centres. In partnership with King’s College London we have dedicated clinical research facilities including an MHRA accredited Phase I clinical trials unit.
Patients are at the heart of everything we do and we pride ourselves on ensuring the best possible patient experience as well as safe, high quality care. We are proud to have one of the lowest mortality rates in the NHS. Following a comprehensive Care Quality Commission (CQC) inspection in 2019 we maintained our overall rating of ‘good’. Our adult community services achieved a rating of ‘outstanding’.
The commitment of our 23,500 staff is key to our success. We are one of the largest local employers and we aim to develop and support all our staff so they are able to deliver high quality, safe and efficient care. The 2019 NHS staff survey results show that we have one of the most engaged and motivated workforces in the NHS. We know this has a positive impact on the care provided to our patients.
We have one of the most ambitious capital investment programmes anywhere in the NHS.
Job overview
We are seeking to appoint a highly motivated Senior Genomics Technician to join the Genomics Research Platform and Single Cell Laboratory within the R&D Department at Guy’s and St Thomas’ NHS Foundation Trust.
Our laboratory employs state-of-the-art genomics technologies to accelerate the translation of research into clinical applications. This is an exciting opportunity for an individual with a strong interest in genomics to contribute to cutting-edge research projects.
The successful candidate will play a key role in supporting our genomics service provision, enabling both academic and clinical research projects. Experience is next-generation sequencing (NGS) is essential, and experience with single-cell or spatial transcriptomics technologies is highly desirable. In this role, you will contribute to advancing innovative research with the ultimate aim of improving patient outcomes.
Advert
As a Senior Genomics Technician, you will undertake scientific projects using a wide range of genomics workflows, driving experiments in bulk-cell sequencing, single-cell analysis, and spatial transcriptomics, providing critical insights for our research objectives. You will play a pivotal role in the optimisation and validation of R&D workflows, evaluating and integrating emerging, cutting-edge technologies into our core pipeline. Working within a collaborative team, you will provide essential technical support and mentorship, ensuring that high-quality data and project outputs are delivered with precision and efficiency.
You will hold at least a BSc (or equivalent) in Biology/Life Sciences or relevant discipline plus experience gained through working in a research/service lab. Knowledge, skills and experience in genomics techniques is essential.
Key responsibilities:
- Workflow execution: Perform end-to-end genomics experiments, from sample preparation to library construction to sequencing, using state-of-the-art platforms.
- Innovation and R&D: Contribute to the development and refinement of lab protocols to enhance sensitivity, throughput and data quality.
- Technical expertise: As the technical expert in genomics workflows, provide training and guidance to junior team members, service users and collaborators.
- Operational Excellence: Maintain rigorous quality control standards and manage project timelines to ensure seamless delivery of results.
Working for our organisation
The Genomics Research Platform at Guy’s & St Thomas’ NHS Foundation Trust (GSTFT) and King’s College London (KCL) is a premier collaboration between one of the UK’s largest and most successful NHS Trusts and a world-leading research university.
Operating as both a specialist service provider and a dedicated R&D facility, the Platform bridges the gap between innovative science and clinical application. Our multidisciplinary team of highly trained scientists possesses deep expertise in single-cell genomics and Next-Generation Sequencing (NGS), supported by a streamlined bioinformatics service to facilitate a broad range of high-impact translational research studies.
We are seeking a candidate for this exciting and challenging role who possesses a robust technical background, a commitment to laboratory excellence, and strong communication skills to support our evolving research portfolio.
Detailed job description and main responsibilities
The Genomics Research Platform, a prestigious collaboration between Guy’s & St Thomas’ NHS Foundation Trust (GSTT) and King’s College London (KCL), is seeking a highly motivated Senior Genomics Technician. This permanent position offers an exciting opportunity to work at the forefront of a rapidly evolving field, contributing to both day-to-day service provision and innovative R&D projects.
As a key member of our specialist team, you will utilise a range of advanced molecular biology techniques to process samples using the latest genomics platforms. This role is ideal for a detail-oriented individual looking to advance their career within a high-impact, multidisciplinary environment that bridges clinical excellence and world-class research.
Main Duties and Responsibilities
- Service Provision: Deliver high-quality genomics services to platform users, including single-cell transcriptomics profiling, spatial transcriptomics, and bulk DNA/RNA sequencing.
- Operational Excellence: Maintain meticulous records of all laboratory work and service operations for assigned projects, ensuring full traceability and data integrity.
- Collaboration & Communication: Work synergistically with team members and key stakeholders across GSTT and KCL to ensure a streamlined and efficient service.
- Research & Development: Actively contribute to the development and refinement of new Standard Operating Procedures (SOPs) and experimental protocols.
- Scientific Engagement: Participate in group meetings, contribute to data discussions, and present experimental findings to the wider team.
Qualifications and Experience
- BSc/MSc/PhD in Biomedical Science or an equivalent discipline with a proven track record in molecular biology workflows.
- Minimum of 3 years of experience in genomics/molecular biology, specifically within a research or service laboratory environment.
- Hands-on experience in manual or automated library preparation for Next-Generation Sequencing (NGS).
- Ability to strictly follow SOPs and worksheets with exceptional attention to detail to ensure reproducible results.
- Proven ability to work independently and complete complex projects within defined timelines and budgetary constraints.
- A fast learner who is receptive to specialised training and comfortable working under close supervision during the initial training period.
Guy’s and St Thomas’ celebrates, respects and values the diversity of its staff and patients. We review our policies, procedures and practices to ensure that all employees, patients and carers are treated equitable according to their needs. We are actively committed to ensuring that no one who applies for a job, works or study’s at the Trust, or accesses our services is discriminated against on the grounds of race, ethnicity, nationality, disability, religion or belief, age, gender identity , gender reassignment, sexual orientation, pregnancy and maternity/paternity, or marital/civil partnership.
Applications are welcomed from applicants with a disability. We can make reasonable adjustments and offer support and advice in a variety of ways throughout the application process. Equality of opportunity is our policy.
As an organisation we are committed to developing our services in ways that best suit the needs of our patients. This means that some staff groups will increasingly be asked to work a more flexible shift pattern so that we can offer services in the evenings or at weekends.
Flexible working
We are committed to supporting all employees to achieve a healthy work life balance and to work in a way that is best for them and our patients. We will consider all requests to work flexibly, taking in to account the individual’s personal circumstances as well the needs of the service. We encourage all prospective applicants to discuss their individual circumstances with the recruiting manager as part of the on-boarding process.
Due to recent changes in the UK immigration rules which affect Skilled Worker Visas, Global Business Mobility, Higher Skill Level and Increased Salary Thresholds, please ensure that you are able to meet the requirements to live and work in the UK before applying. Further information about eligibility is available on the UK Government website.
Your e-mail address is important to us - We communicate to all job applicants via the e-mail address which has been provided on the application form. Please ensure that you check your e-mail on a regular basis.
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Person specification
Qualifications/Education
Essential criteria
- Degree level education in relevant discipline (e.g. Biology, Life Sciences)
Desirable criteria
- Masters in relevant discipline (e.g. Biology, Life Sciences)
Experience
Essential criteria
- Experience in library preparation for NGS
- Experience in wet-lab molecular workflows (e.g. DNA/RNA extractions, qPCR, sample QC)
- Experience in operating Illumina sequencing platforms
- Experience in service provision lab
Desirable criteria
- Experience in single cell NGS workflows
- Experience in spatial transcriptomics workflows
- Experience in long read sequencing technologies (e.g. Nanopore or PacBio)
Skills
Essential criteria
- Be able to follow standard operating procedures
- Ability to prioritise and meet deadlines
Desirable criteria
- Operating complex equipment (e.g. Tapestation, Bioanalyser, Covaris etc)
Further details / informal visits contact
- Name
- Pawan Dhami
- Job title
- Head of Genomics Research Platform
- Email address
- [email protected]
- Telephone number
- 020271887997
No longer accepting applications
Sorry, this vacancy is no longer accepting applications.
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